This page describes my habilitation thesis with the title:

Flexible and Rigid Non-glucose Cyclooligosaccharides:
Synthesis, Structure, and Properties

• Lecture - Slides
• Lecture - Extras
• Thesis - Table of Contents

 

The thesis is written in English, the full text is available as PDF-file (6.8 MBytes):

Habilitation Thesis
PD Dr. Stefan Immel (PDF)

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Habilitation Thesis - Slide

Flexible and Rigid Non-glucose Cyclooligosaccharides: Synthesis, Structure, and Properties
Introduction			1
Synopsis			3
Chapter 1 - From Cyclodextrins to Amylose: Structures and Lipophilicity Patterns			19
	Topography of the 1:1 α-Cyclodextrin - Nitromethane Inclusion Complex T. Nakagawa, S. Immel, F. W. Lichtenthaler, and H. J. Lindner, Carbohydr. Res. 2000, 324, 141-146.		21
	The Hydrophobic Topographies of Amylose and its Blue Iodine Complex S. Immel and F. W. Lichtenthaler, Starch/Stärke 2000, 52, 1-8.		27
Chapter 2 - Per-2,3-anhydro-α-cyclomannin			35
	Structure and Lipophilicity Profile of 2,3-Anhydro-α-cyclomannin and its Ethanol Inclusion Complex S. Immel, K. Fujita, H. J. Lindner, Y. Nogami, and F. W. Lichtenthaler, Chem. Eur. J. 2000, 6, 2327-2333.		37
	The 2,3-Anhydro-α-cyclomannin - 1-Propanol Hexahydrate: Topography, Lipophilicity Pattern, and Solid-state Architecture S. Immel, F. W. Lichtenthaler, H. J. Lindner, K. Fujita, M. Fukudome, and Y. Nogami, Tetrahedron: Asymmetry 2000, 11, 27-36.		45
Chapter 3 - α-Cycloaltrin			55
	Synthesis, Structure, and Conformational Features of α-Cycloaltrin: a Cyclooligosaccharide with alternating 4C1 and 1C4 Pyranose Chairs Y. Nogami, K. Nasu, T. Koga, K. Ohta, K. Fujita, S. Immel, H. J. Lindner, G. E. Schmitt, and F. W. Lichtenthaler, Angew. Chem. 1997, 109, 1987-1991; Angew. Chem. Int. Ed. Engl. 1997, 35, 1899-1902.		57
	Solution Geometries and Lipophilicity Patterns of α-Cycloaltrin S. Immel, K. Fujita, and F. W. Lichtenthaler, Chem. Eur. J. 1999, 5, 3185-3192.		61
	Inclusion Complexes of Cycloaltrins S. Immel, K. L. Larsen, unpublished results.		69
Chapter 4 - Mono-altro-β-cyclodextrin			73
	Guest-induced Conformational Change in a Flexible Host: Mono-altro-β-cyclodextrin K. Fujita, W.-H. Chen, D.-Q. Yuan, Y. Nogami, T. Koga, T. Fujioka, K. Mihashi, S. Immel, and F. W. Lichtenthaler, Tetrahedron: Asymmetry 1999, 10, 1689-1696.		75
Chapter 5 - Cyclofructins and Cyclogalactofuranosides			83
	Cyclofructins with Six to Ten β(1→2)-linked Fructofuranose Units: Geometries, Electrostatic Profiles, Lipophilicity Patterns, and Potential for Inclusion Complexation S. Immel, G. E. Schmitt, and F. W. Lichtenthaler, Carbohydr. Res. 1998, 313, 91-105.		85
	Conformations and Lipophilicity Profiles of some Cyclic β(1→3)- and β(1→6)-linked Oligogalactofuranosides H. Gohlke, S. Immel, and F. W. Lichtenthaler, Carbohydr. Res. 1999, 321, 96-104.		101
Chapter 6 - Cyclodextrin-derived Crown Acetals			111
	Synthesis and Molecular Geometry of an Achiral 30-Crown-12 Polyacetal from α-Cyclodextrin S. Immel, T. Nakagawa, H. J. Lindner, and F. W. Lichtenthaler, Chem. Eur. J. 2000, 6, 3366-3371.		113
	Hydroxymethyl-substituted Crown Acetals with 35-C-14 and 40-C-16 Skeletal Backbones: Synthesis and Molecular Geometries S. Immel, F. W. Lichtenthaler, H. J. Lindner, and T. Nakagawa, Tetrahedron: Asymmetry 2001, 12, 2767-2774.		119
	Large-ring Crown Acetals from Cyclodextrins T. Nakagawa, S. Immel, H. J. Lindner, and F. W. Lichtenthaler, Proc. 10th Int. Symp. Cyclodextrins (Ed.: J. Szejtli), Mia Digital Publ., Ann Arbor, Michigan, 2000, pp. 18-23.		127
	Flexible Non-glucose Cyclooligosaccharides S. Immel, Proc. 10th Int. Symp. Cyclodextrins (Ed.: J. Szejtli), Mia Digital Publ., Ann Arbor, Michigan, 2000, pp. 24-31.		133
Chapter 7 - Rigidified Bridged Cyclodextrins			141
	Two Stereoisomeric 3I,2II-Anhydro-α-cyclodextrins: A Molecular Dynamics and Crystallographic Study S. Immel, K. Fujita, M. Fukudome, and M. Bolte, Carbohydr. Res. 2001, 336, 297-308.		143
	The First Successful Crystallographic Characterization of a Cyclodextrin Dimer: Efficient Synthesis and Molecular Geometry of a Doubly Sulfur-bridged β-Cyclodextrin D.-Q. Yuan, S. Immel, K. Koga, M. Yamaguchi, and K. Fujita, Chem. Eur. J. 2003, 9, 3501-3506.		155
Chapter 8 - Molecular Modelling of Saccharides			161
	Atropdiastereoisomers of Ellagitannin Model Compounds: Configuration, Conformation, and Relative Stability of D-Glucose Diphenoyl Derivatives S. Immel, K. Khanbabaee, Tetrahedron: Asymmetry 2000, 11, 2495-2507.		163
	Metabolism of Sucrose and Its Five Linkage-isomeric α-D-Glucosyl-D-fructoses by Klebsiella pneumoniae J. Thompson, S. A. Robrish, S. Immel, F. W. Lichtenthaler, B. G. Hall, and A. Pikis, J. Biol. Chem. 2001, 276, 37415-37425.		177
	Metabolism of Sucrose and Its Five α-D-Glucosyl-D-fructose Isomers by Fusobacterium mortiferum A. Pikis, S. Immel, S. A. Robrish, and J. Thompson, Microbiology 2002, 148, 843-852.		189
Chapter 9 - Molecular Graphics			199
	MolArch+ - Molecular Architecture Modelling Program S. Immel, http://sugar.oc.chemie.tu-darmstadt.de/ak/immel/.		201
Conclusion			211
	Concluding Remarks		213
Appendix			215
	List of Publications		217
	Poster Presentations and Conference Contributions		221
	Oral Presentations		223
	Curriculum Vitae		225