|TUD Organische Chemie||Immel||Publications||Papers||Abstract 06||View or Print (this frame only)|
Frieder W. Lichtenthaler and Stefan Immel
Tetrahedron: Asymmetry 1994, 5, 2045-2060.
A molecular modeling study of the (1→4)-linked cyclooligosaccharides containing five and six α-D-glucose, α-D-mannose, and β-D-galactose units, respectively, provides a clear conception of their overall conformations, their contact surfaces, and their cavity proportions. A MOLCAD-based generation of their molecular lipophilicity potential (MLP's) gives a lucid picture of their hydrophobic and hydrophilic surface areas, and hence, a first estimation of their inclusion properties.
Additional Graphics: Cyclodextrin Isomers